COMPARISON OF THE EFFICIENCY OF NON-PENETRATING DEEP SCLERECTOMY AS A STANDALONE SURGERY AND MODIFIED NON-PENETRATING DEEP SCLERECTOMY IN COMBINATION WITH AB INTERNO ENDOTRABECULECTOMY
Aim. To compare the hypotensive effect of non-penetrating deep sclerectomy (NPDS) as a standalone surgery and non-penetrating deep sclerectomy in combination with dosed endotrabeculectomy in patients with primary open-angle glaucoma.
Materials and Methods. 27 patients (27 eyes) with primary open-angle glaucoma were under our follow-up. In the first group (15 patients) we performed a non-penetrating deep sclerectomy, in the second group (12 patients) - a combined surgery.
Results and Discussion. When comparing values, we found that the difference between the preoperative and postoperative IOP, as well as the preoperative and postoperative amount of topical antihypertensives used, was significant up to the 12th month inclusive in both groups (p<0.05). No significant difference was found when comparing IOP values between two groups in the same follow-up periods. However, there was a difference in the amount of topical intraocular pressure-lowering agents used by two groups in the 12th month of follow-up.
Conclusions. Non-penetrating deep sclerectomy, both standalone and in combination with endotrabeculectomy, has a significant hypotensive effect in patients with primary open-angle glaucoma during 12 months of follow-up, however, patients of the first group instilled a higher amount of topical antihypertensives in the 12th month of follow-up, which makes us consider the hypotensive effect of the combined surgery to be higher.
Trivli A. et al. Primary open angle glaucoma genetics: The common variants and their clinical associations (Review). Mol. Med. Rep. Mol Med Rep, 2020. Vol. 22, No 2. P. 1103-1110.
Kang J.M., Tanna A.P. Glaucoma. Med. Clin. North Am. Med Clin North Am, 2021. Vol. 105, No 3. P. 493-510.
Sihota R. et al. Simplifying "target" intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma Indian J. Ophthalmol. Wolters Kluwer Medknow Publications, 2018. Vol. 66, № 4. P. 495.
Bertaud S. et al. [Primary open-angle glaucoma] La Rev. Med. interne. Rev Med Interne, 2019. Vol. 40, No 7. P. 445-452.
Modern surgery of primary open-angle glaucoma. Opting for minimally invasive surgeries [Electronic resource]. URL: https://library.gov.ua/suchasna-hirurgiya-pervynnoyi-vidkrytokutovoyi-glaukomy-perehid-do-miniinvazyvnyh-operatsij/ (accessed: 06.02.2022).
Vila-Mascarell E. et al. Spurectomy: A novel modification of non-penetrating deep sclerectomy. Arch. Soc. Esp. Oftalmol. Arch Soc Esp Oftalmol (Engl Ed), 2021. Vol. 96, No 4. P. 195-201.
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